At an up-and-down 3-4, the reigning NFC champion San Francisco 49ers can’t be reliably counted on as a bona fide contender.

The San Francisco 49ers had their worst fears confirmed on Monday. Per Jordan Schultz of Fox Sports, tests determined that ...

The San Francisco 49ers and fantasy football managers won't have star wide receiver Brandon Aiyuk at their disposal anytime soon following his knee injury.

The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, and they have also ...

Multiple national reporters have confirmed that Aiyuk’s ACL is torn, along with his MCL, and there may be other damage. Aiyuk ...

Other stars, including Cleveland's Deshaun Watson, Washington's Jayden Daniels and San Francisco's Brandon Ayiuk all left ...

The 49ers need to make a move to address their wide receiver situation after Brandon Aiyuk's ACL & MCL tear.

The Brandon Aiyuk announcement from the 49ers comes at one of the worst possible times for the team, as they are 3-4 and ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee.

The strength of the San Francisco 49ers’ offense the past few seasons has been the number of dynamic playmakers that makes it ...

The injury is the latest to hit a star player for the 49ers, who have been missing All-Pro running back Christian McCaffrey ...

It was another difficult day on the injury front including the QB3 entering Week 7 and one of last year's top wideouts. We ...