Yordan Alvarez drew a leadoff walk, setting the table for the middle of a Houston Astros lineup seeking a breakthrough in such situations. Three hitters strode to the plate. Each represented the potential tying run.

After posting a sub-.500 road record in their first season under manager Bob Melvin in 2024, the San Francisco Giants entered this campaign pressed to start on a positive note away from Oracle Park. With their 3-1 interleague victory at the Houston Astros on Tuesday,

Pregame analysis and predictions of the San Francisco Giants vs. Houston Astros MLB game to be played on April 2, 2025 on ESPN.

Wilmer Flores hit his third homer of the season and drove in four runs to lead the San Francisco Giants to a 7-2 win over the Houston Astros.

Wilmer Flores homered again and Luis Matos and LaMonte Wade Jr. also went deep to lead the San Francisco Giants to a 6-3 win over the Houston Astros to complete a three-game sweep.

Logan Webb worked seven strong innings, Heliot Ramos clubbed his third home run, and the visiting San Francisco Giants earned an interleague series victory over the Houston Astros with a 3-1 win on Tuesday.

Wilmer Flores already matches his home run total from 2024 with a another long ball for the Giants. ESPN BET Sportsbook is owned and operated by PENN Entertainment, Inc. and its subsidiaries ('PENN').

Wilmer Flores slugged his fourth home run of the season, Heliot Ramos extended his extra-base hit streak and the visiting San Francisco Giants completed a three-game interleague sweep of the Houston Astros with a 6-3 victory on Wednesday.

Alex Pavlovic highlights five things we learned about the 2025 San Francisco Giants on their season-opening road trip.