President Donald Trump’s pick to lead the Commerce Department said Mexico and Canada can avoid new tariffs due this weekend if they clamp down on border security — while also signaling that Trump is likely to impose widespread new levies to return manufacturing to US soil.

Having already forced Colombia to accept deportees by threatening a 25% tariff, President Donald Trump is readying the same move against Canada and Mexico as soon as Saturday. But this time, the stakes are higher and many economists surveying the possible damage doubt Trump would be comfortable with what they say would be self-inflicted wounds from the tariffs.

General Motors, the largest producer of cars in Mexico, won’t provide details on how it would react if President Trump imposes 25 percent tariffs from the two countries.