Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells ...

A gastrointestinal oncologist told Newsweek that the early-stage findings are a “major step forward” in targeting colon ...

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew ...

Loss of GATA6—a transcription factor that controls which genes are turned on or off—can reprogram colorectal cancer cells ...

Researchers found that loss of GATA6 reprograms colorectal cancer cells into flexible, fetal-like states that can spread to ...

Epigenetic drift is a key feature of aging and is associated with age-related diseases including cancer, yet the underlying molecular mechanisms remain unclear. Here, by analyzing DNA methylation and ...

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals. These are the findings published on 3 December in ...

Researchers have long suspected that the gut microbiome—the community of bacteria and other microorganisms living in the ...

It may be sheer good fortune that some people exposed to cancer-causing agents do not develop the disease, study suggests ...

The underlying mechanism of the transformation of a normal cell into a cancerous cell lies in the acquisition of faults in ...

Gastric cancer precursors demonstrate highly-variable rates of progression toward neoplasia. Certain high-risk precursors, such as gastric intestinal metaplasia with advanced histologic features, may ...

Small intestine cancer is rare, with adenocarcinomas being the most common type, often occurring in the duodenum. Diagnosis involves imaging, endoscopy, and biopsy, with staging determined by the TNM ...