Most cases of autoimmune lymphoproliferative syndrome (ALPS) are associated with heterozygous mutations in the genes encoding CD95 (Fas receptor), CD95 ligand and the apoptotic enzyme caspase-10.
Transition between cell states of sensitivity reveals molecular vulnerability of drug-tolerant cells
Cancer cells evade apoptosis by transitioning between cell states of drug-sensitivity. Necroptosis vulnerability state was ...
Background. Paracoccidioides brasiliensis is equipped with an arsenal of virulence factors that are crucial for causing infection. Our group previously defined the NLRP3 inflammasome as a mediator of ...
The c-Jun N-terminal kinase (JNK) signaling pathway mediates adaptation to stress signals and has been associated with cell death, cell proliferation, and malignant transformation in the liver.
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