Objective Less than half of servicewomen report loss of menses during initial military training. However, self-reported menstrual status may not accurately reflect hypothalamic-pituitary-ovarian (HPO) ...

The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a ...

Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.

Picking the Right Patient for Human Epidermal Growth Factor Receptor 3–Targeted Therapy in Platinum-Resistant Ovarian Cancer The Oncology Grand Rounds series is designed to place original reports ...

Changes clinical practice: Adults who received cranial radiotherapy for nonpituitary tumors should have their hypothalamic-pituitary axis periodically evaluated. This is the first meta-analysis of ...

Testing of hypothalamic-pituitary-end-organ function has advanced remarkably in recent years. As newer tests are compared to the standard ones, it has become apparent that no single test can determine ...

The hypothalamus–pituitary–target gland axis has been recognized as a fundamental functional framework of the mammalian endocrine system. The anterior pituitary gland synthesizes and secretes multiple ...

This article was reviewed by Darragh O’Carroll, MD. Key Takeaways: Enclomiphene boosts natural testosterone production by stimulating the hypothalamic-pituitary-gonadal (HPG) axis, making it a ...