Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population. This syndrome encompasses a range of conditions, including obesity, type 2 diabetes ...

Specialized brain cells in the hypothalamus act as a disposal route for tau protein, shuttling it from cerebrospinal fluid into the bloodstream. When those cells break down, tau accumulates in the ...

Hypothalamic obesity (HyOb) is a type of obesity caused by damage to the brain’s hunger-regulating function. While there’s no cure, proper treatment can help improve your daily life and prevent ...

Please provide your email address to receive an email when new articles are posted on . Setmelanotide was linked to reduction in BMI at 52 weeks compared with placebo for patients with acquired ...

Researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease ...

Central hypothyroidism is a rare disorder that occurs when an otherwise healthy thyroid doesn't produce enough hormone due to problems that originate in the pituitary gland, the hypothalamus, or both.

BMI reduction achieved in all patients (N=142) at 52 weeks, including 12 Japanese patients and 10 supplemental patients with acquired hypothalamic obesity -- -- March 20, 2026 PDUFA goal date for sNDA ...

How do mammals manage to eat in situations that cause anxiety, step into exposed spaces, or slow down when anxiety drives them to keep moving? A new study pinpoints a leptin-sensitive circuit in the ...