Lipid nanoparticles (LNPs ... These must be tested individually for purity and the final composition determined. The CAD detection is not only sensitive for these non-UV absorbing compounds ...

Peer and his team encoded the anti-inflammatory protein interleukin-10 into mRNA, encapsulated it in lipid nanoparticles with a composition different from those typically used (such as in mRNA ...

Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system. Nature Materials , 2025; DOI: 10.1038/s41563-024-02114-5 Cite This Page : ...

Pancreatic cancer remains one of the most challenging tumors to treat, partly because it is often discovered at advanced ...

DNA delivery using lipid nanoparticles results in severe toxicity in mice. However, we find that the incorporation of endogenous anti-inflammatory lipids into the lipid nanoparticles mitigates ...

the current delivery systems available—viral vectors and lipid nanoparticles (LNPs)—pose unique challenges for gene therapy applications. For example, immune responses against viruses limit these ...

Blood samples were analyzed for lipid profiles ... Selima et al, Effect of gold nanoparticles treatment on rats-induced obesity by evaluating body-composition directly and indirectly via ...

A combination of mRNA and a new lipid nanoparticle could help heal damaged lungs, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Viruses ...

Researchers at the Icahn School of Medicine at Mount Sinai say they have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection ...

New York, NY [February 17, 2025]—Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via ...