Photos and short interviews with Tenderloin residents who discuss living in a place that many identify with the fentanyl ...

A condominium that was listed for $3.25 million in one of the most dangerous neighborhoods in San Francisco has found a buyer ...

City Hope Cafe operates a free cafe and a sense of normalcy in the heart of a troubled inner-city neighborhood.

San Francisco is ramping up its efforts to battle a deadly fentanyl crisis with the city's new mayor declaring a state of ...

The Tenderloin Museum, a scrappy cultural space and living history center celebrating the city’s perennial underdog neighborhood, is planning a major expansion that will triple its size and add a ...

Kevin Fagan is retiring from the San Francisco Chronicle. His new book "The Lost and The Found" details stories of unhoused people reuniting with loved ones after years on the street.

I blame AI. — Timothy Karoff, SFGATE culture reporter The folks who say art is dead in San Francisco haven’t ever been out in the Tenderloin on a First Thursday. Every month, a dozen art ...

SFPD arrested 59 in a drug operation, recovering suspected cocaine and targeting individuals with outstanding warrants.

(AP Video: Haven Daley) Volunteers hand out numbers to pet owners waiting in line at a free dog vaccine clinic to combat a canine Parvovirus outbreak on Monday, Feb. 3, 2025, in the Tenderloin in San ...