Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably ...

Arren Bar-Even drove a new way to engineer metabolism; his former collaborators and students are continuing the work ...

In a recent study published in Nature Communications, researchers at Karolinska Institutet report that the molecular ...

The study of pediatric metabolic diseases often highlights the complexity of biochemical pathways and physiological processes disrupted in young patients.

Pathway analysis is a frequent step in studies involving gene or protein expression data, but most of the available pathway methods are designed for simple case versus control studies of two sample ...

Deregulated pyrimidine metabolism (PyMet) contributes to various tumorigenic features of cancer, including chemoresistance and epithelial-to-mesenchymal transition. However, cancer often encompasses ...