Phagocytes such as macrophages and neutrophils contain multiple lysosomes, which possess a variety of digestive enzymes. Upon stimulation, phagocytes secrete these digestive enzymes through a process ...

Mononuclear phagocytes can both promote and inhibit inflammation. A team has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different ...

The engulfment ability of a phagocyte is controlled by its mitochondrial membrane potential (MMP), according to a study by Ravichandran and colleagues. The authors reasoned that the 'ingestion' of ...

For many of us, adding salt to a meal is a perfectly normal thing to do. We don't really think about it. But actually, we should. As well as raising our blood pressure, too much salt can severely ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 29 (Jul. 17, 2007), pp. 12075-12080 (6 pages) The contribution of CCR6 and phagocyte recruitment to the ...

Immune cells in the brain can act like good soldiers in the fight against Alzheimer’s disease, gobbling up Aβ and keeping the disease at bay. Or, they can stir up trouble by releasing harmful ...

Since Metchnikoff's realization, in the 1880's, of the potential for the host-parasite relation 1 of the process he termed "phagocytosis," countless studies have been carried out in that field.

ONE designates as phagocytes cells endowed with the ability to ingest particulate matter such as bacteria, cellular debris and colloidal dyes. The ingested material may or may not be digested within ...

For many of us, adding salt to a meal is a perfectly normal thing to do. We don't really think about it. But actually, we should. As well as raising our blood pressure, too much salt can severely ...

Since the discovery that variants in the microglial receptor TREM2 triple the risk of Alzheimer’s disease, researchers have tried to figure out why. Studies conflict on what TREM2 does in AD models, ...

The Journal of Infectious Diseases, Vol. 172, No. 4 (Oct., 1995), pp. 1028-1034 (7 pages) The effects of recombinant human macrophage colony-stimulating factor (M-CSF) on antifungal activity of human ...