In the past decade, high-throughput structure determination with X-ray crystallography has demonstrated its value as a tool not just for optimizing lead compounds, but also for lead discovery.

Modern biological sciences are enriched by the revolution in structural biology. Advances in techniques such as electron microscopy (EM), X-ray crystallography and NMR, coupled with modern biophysical ...

The Center for Integrative Structural Biology (abbreviated as ‘iSB’) was created in 2024 to integrate and expand expertise in Structural Biology at UAB. Our researchers use quantitative structural ...

In our studies we use integrated computational, biochemical and structural methods including X-ray crystallography ... We are also interested in synthetic biology, where life processes are harnessed ...