The Wake Forest Institute for Regenerative Medicine (WFIRM) researchers who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their ...

Telomerase plays a pivotal role in maintaining chromosome integrity by adding telomeric repeats to the ends of chromosomes. Its reactivation in a vast majority of cancers makes it an invaluable ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

Prognostic and Predictive Factors for Patients With Metastatic Breast Cancer Undergoing Aggressive Induction Therapy Followed by High-Dose Chemotherapy With Autologous Stem-Cell Support PURPOSE: ...

Evaluation of quality of life in patients treated with resection and reconstruction of the upper or lower limb for bone sarcomas. Background: Gastrointestinal stromal tumors (GISTs), the most common ...

It is difficult to underestimate the importance of telomerase, an enzyme that is the hallmark of both aging and the uncontrolled cell division associated with cancer. In an effort to understand and ...

According to Brunner, mutations in MDS progenitor cells cause impaired production of red blood cells, and emerging research is showing the role of telomerase in causing anemia and dependence on red ...

Research in Developmental Cell shows that TIN2 preferentially binds to TRF1 and prevents Fbx4-mediated degradation. Researchers have identified a cellular interaction that could hint at new approaches ...

Scientists investigate human telomere length to elucidate aging and diseases such as cancer and neurodegenerative disorders. In normal mammalian cells, a small telomeric DNA segment is lost after each ...