CAMBRIDGE, MA -- Measuring the toxic effects of chemical compounds on different types of cells is critical for developing cancer drugs, which must be able to kill their target cells. Analyzing cell ...
In renal cell carcinoma, transglutaminase 2 (TGase 2) crosslinks p53 in autophagosomes, resulting in p53 depletion and the tumor’s evasion of apoptosis. Inhibition of TGase 2 stabilizes p53 and ...
Using the tetrazolium salt XTT (Na,3′-[(phenylamino)-carbonyl]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzenesulfonic acid hydrate) as a sensitive and ...
Biological engineers have devised a toxicity test that can measure chemical effects on cell survival with much greater sensitivity than the tests commonly used today. The MicroColonyChip could make it ...
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