The reversible conjugation of ubiquitin chains to protein substrates regulates almost every cellular process. Ubiquitin chains can be assembled via one of the seven ubiquitin Lys residues (which are ...

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' channel-plugging mechanism. The findings boost the ...

One of the major advantages of 3D printing is the ability to quickly test and then iterate on mechanical designs. [gzumwalt] does a lot of this, and has recently been working on various versions of a ...