An anatomically defined retinotopy atlas was applied to the inflated cortical surface for each participant in order to delineate the borders of V1, V2 and V3, and also each degree of eccentricity up ...

This study demonstrates that plant and fruit volatiles can be organized according to a low-dimensional hyperbolic map, and that within this map exist trajectories that correspond to important ...

Programmed Cell Death Protein-1 (PD-1) represents endogenous mechanisms of negative immunoregulation. While the modulation of effector functions has been the major focus of PD-1 research, quick PD-1 ...

This valuable report describes the changing antiviral activity of IFIT1 across mammals and in response to distinct viruses, likely as a result of past arms races. One of the main strengths of the ...

Researchers have discovered a new plant seed fossil, Alasemenia, one of the earliest known examples of a winged seed.

The advent of large-scale sequencing in both development and disease has identified large numbers of candidate genes that may be linked to important phenotypes. Validating the function of these ...

In this important study, the authors used a zebrafish model and scRNAseq analysis to show that a subset of keratinocytes within melanoma microenvironment highly up-regulate Twist and undergo ...

This important study shows that sound exposure enhances drug delivery to the cochlea via outer hair cell electromotility acting as a "fluid pump". Although others have proposed that electromotility ...

Mounting evidence showed that the genetic association of ORMDL3 (ORMDL Sphingolipid Biosynthesis Regulator 3) gene polymorphisms with bronchial asthma and various inflammatory disorders. Yet its role ...

The fusion of two genes on chromosome 12 – NAB2 and STAT6 – has been found in a rare form of cancer, known as a solitary fibrous tumor, which can form in almost any part of the body ( Thway et al., ...

In mammals, autophagosome formation, a central event in autophagy, is initiated by the ULK complex comprising ULK1/2, FIP200, ATG13, and ATG101. However, the structural basis and mechanism of the ULK ...

A critical review of the limitations posed by current preclinical animal models of Alzheimer's disease and of the oversimplistic assumptions proposed by the amyloid cascade hypothesis (ACH).