Single-cell analysis fails to find a functional link between the organization of chromatin domain organization and gene activity.

Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" ...

Every cell in your body faces the same engineering puzzle: how to cram roughly two meters of DNA into a nucleus just a few ...

Anti-cancer drugs often fail, but a new discovery about how two key proteins interact with DNA is changing that, serving as a ...

The immune system's B cells create antibodies that can mount a response against just about anything—either destroying a ...

Cancer drugs known as BET inhibitors once looked like a breakthrough, but in real patients they’ve often fallen short. New ...

PerturbFate can systematically map how diverse disease-associated genetic variations reshape cells to understand complex diseases, like cancer.

New study uncovers triplex-mediated transcriptional activation driving tumor suppression in HCC Hepatocellular carcinoma (HCC ...

Why is the timing of trauma so important? New research shows that estrogen levels in the hippocampus at the moment of stress ...