The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, but they may have lost a ...

San Francisco 49ers wide receiver Brandon Aiyuk exited Sunday's loss against the Kansas City Chiefs during the first half ...

Chiefs defenders Justin Reid and Chamarri Conner sandwiched the receiver on a tackle in the waning seconds of the first half.

San Francisco 49ers head coach Kyle Shanahan discusses Sunday’s 28-18 loss to the Kansas City Chiefs, believes that Brandon ...

San Francisco 49ers wide receiver Brandon Aiyuk might have suffered a significant injury in Sunday's loss to the Kansas City ...

Brandon Aiyuk was carted off at the end of the first half against the Chiefs after a crunching tackle messed up his leg.

Brandon Aiyuk went down with a right knee injury in Sunday's 28-18 loss to the Kansas City Chiefs that coach Kyle Shanahan ...

The San Francisco 49ers lost standout receivers Brandon Aiyuk and Deebo Samuel during Sunday's 28-18 loss to the visiting ...

Already missing one of their top three receivers, the San Francisco 49ers lost wideouts Deebo Samuel and Brandon Aiyuk to an ...

San Francisco 49ers legend Steve Young referenced some outdated school punishment methods when he described the Kyle Shanahan ...

The San Francisco 49ers are fearing star receivier Brandon Aiyuk has suffered a torn ACL after being carted off against the Kansas City Chiefs on Sunday ...

49ers wide receiver Brandon Aiyuk has been ruled out for the remainder of Sunday's game against the Chiefs with a knee injury. Aiyuk was injured on a 15-yard reception at the tail end of the second ...