The San Francisco 49ers sustained a season-ending knee injury in their 28-18 loss to the Kansas City Chiefs on Sunday, tests ...

The San Francisco 49ers will have to move forward without one of their top players on offense after Brandon Aiyuk went down ...

Samuel, Jennings and George Kittle are set to carry the bulk of the burden in the passing game with Aiyuk out of the picture, ...

San Francisco 49ers receiver Ricky Pearsall was pushed into a bigger role than anticipated in his NFL debut Sunday.

The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, and they have also ...

The 49ers are dealing with a well-known injury to running back Christian McCaffrey, but more injuries decimated their ...

When replays showed the hit on Brandon Aiyuk's leg during the Week 7 matchup between the San Francisco 49ers and Kansas City ...

The San Francisco 49ers had their worst fears confirmed on Monday. Per Jordan Schultz of Fox Sports, tests determined that ...

Mahomes has more interceptions (eight) than touchdowns (six) this season and a career-low 82.5 passer rating. But a stingy ...

Talanoa Hufanga, an All-Pro safety in 2022, has played in just one game after recovering from a torn ACL, was felled by a ...

Coby Bryant, practice-squad callup Josh Jobe and rookie Nehemiah Pritchett rose to the occasion while making fill-in starts ...

Concerning picture of Deebo Samuel has fans comparing him to James Harden as he looks out of shape on the field.