At an up-and-down 3-4, the reigning NFC champion San Francisco 49ers can’t be reliably counted on as a bona fide contender.

An MRI confirmed San Francisco 49ers receiver Brandon Aiyuk suffered a torn ACL in Sunday's 28-18 loss to the Kansas City Chiefs, NFL Network Insider Ian Rapoport reported on Monday.

Multiple national reporters have confirmed that Aiyuk’s ACL is torn, along with his MCL, and there may be other damage. Aiyuk ...

The San Francisco 49ers wide receiver sustained a season-ending knee injury in their 28-18 loss to the Kansas City Chiefs on ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee.

The injury is the latest to hit a star player for the 49ers, who have been missing All-Pro running back Christian McCaffrey ...

The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, and they have also ...

The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, and they have also ...

The Seattle Seahawks’ primary rivals, the San Francisco 49ers, might be the only other team in the league that can rival the ...

The San Francisco 49ers had their worst fears confirmed on Monday. Per Jordan Schultz of Fox Sports, tests determined that ...

The 49ers' fear over Brandon Aiyuk's knee injury came to fruition. The star wide receiver has suffered an ACL tear, FOX ...

San Francisco 49ers rookie receiver Ricky Pearsall made his NFL debut exactly 50 days after being shot in the chest during a ...