Gut

Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure

Background Why alcohol-associated liver disease (ALD) resolves after abstinence in most people but progresses to liver ...
Gut

CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...
Gut

Recovery of HBV-specific B cell function after discontinuation of nucleos(t)ide analogue therapy: new insight and future challenges

In hepatitis B virus (HBV) infection, the capacity to mount a functional virus-specific T-cell response has long been considered the principal, if not the sole, immunological determinant of viral ...
Opinion
GutOpinion

Road to IBD prevention in the Global South: a conceptual framework modelling from non-communicable diseases

IBD is rising worldwide and is now a global disease. With the expanding armamentarium of medical therapies, including biologics and small molecules, there is a decline in hospitalisation rates and IBD ...
Gut

Role of A2 beta casein in milk-induced eosinophilic oesophagitis: novel in-vivo and in-vitro findings

We read with interest the article by Santacroce about personalised medicine in eosinophilic oesophagitis (EoE) and the ...
gut.bmj

Should the China-CLIF framework influence model for end-stage liver disease-based transplant priority in acute-on-chronic liver failure?

We read with interest the multicohort study by Luo et al evaluating the China-CLIF framework for acute-on-chronic liver failure (ACLF) across diverse aetiologies.1 The authors demonstrate that ...
gut.bmj

Pueraria lobata-derived exosome-like nanovesicles alleviate rheumatoid arthritis via targeting Ruminococcus gnavus phenylethylamine production

Background Gut microbiota has been widely recognised as playing a critical role in maintaining immune imbalance and the development of rheumatoid arthritis (RA). As key roles mediating interkingdom ...
gut.bmj

Gut, inflammation and osteoporosis: basic and clinical concepts

1 Christian Doppler Research Laboratory for Gut Inflammation and Department of Medicine, Division of Gastroenterology and Hepatology, Medical University Innsbruck, Austria 2 Department of Medicine “T” ...
gut.bmj

Increased uptake and improved outcomes of bowel cancer screening with a faecal immunochemical test: results from a pilot study within the national screening programme in England

3 NHS Bowel Cancer Screening Midlands and North West Programme Hub, Rugby, UK 4 NHS Bowel Cancer Screening Southern Programme Hub, Guildford, UK 5 University of Surrey, Guildford, UK Correspondence to ...
gut.bmj

Expression of NOD2 in Paneth cells: a possible link to Crohn’s ileitis

1 Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA 2 Department of Medicine, Royal Free and University College Medical ...
gut.bmj

Global consensus statement on the management of pregnancy in inflammatory bowel disease

Background & aims Pregnancy can be a complex and risk filled event for women with inflammatory bowel disease (IBD). High-quality studies in this population are lacking, with limited data on ...