Lecanemab Favors Early Aggregates. Fluorescently labeled lecanemab (green) bound most strongly to soluble Aβ aggregates ...

Do you know a conference you think we should list? Let us know by sending us an email with the details to [email protected].

A drug that has been used for nearly a century to prevent and dissolve blood clots may also delay the onset of Alzheimer’s disease, according to a study in the October 8 Molecular Psychiatry. Heparin ...

Michael Belloy at Washington University in St. Louis noted that the findings could help distinguish between genes that directly affect pathology, and those that instead help maintain cognition in the ...

A top researcher’s fall from grace sends shock waves through the scientific community. Such is the case with neuropathologist Eliezer Masliah, who stands accused of image falsification spanning 26 ...

For example, Huntington’s disease (HD), the first expansion disorder discovered, occurs when a cysteine-arginine-guanine (CAG) trinucleotide in the HTT gene swells to 40 or more repeats. Such ...

The clinical worsening after microglia envelop neurons suggests the phenomenon is harmful, the authors noted. “With disease progression, microglial behavior changes from positive to negative,” ...

In this mouse, TREM2 and the fluorescent protein mKate2 are co-expressed under the control of the endogenous Trem2 promoter, allowing researchers to indirectly assess expression of TREM2 by measuring ...

A group of scientists argue, in a review published in Fluids and Barriers of the CNS earlier this year, that it’s time to adopt a more apt metaphor. Jan Pieter Konsman and Jerome Badaut of the ...