High-resolution cryo-electron microscopy makes it possible to study complex enzymatic processes in detail. With this method, ...

Radiation damage remains the principal limitation in achieving higher resolution in cryo-electron microscopy (cryo-EM), ...

Proteins from 40 kDa to several MDa in size can be studied by this methodology. Very little sample is required for this technique. For cryo-EM the specimen, typically a purified protein sample, is ...

Though it might seem tempting, you probably don’t want to get involved with a TEM. These microscopes operate by shining electrons through a sample onto a phosphor target; the phosphors glow ...

For example, interactions of the electron beam with specific gases can be used to achieve the controlled deposition of materials such as metals or different forms of carbon onto a substrate. This ...

Being an SEM, the sample has to be placed in a high vacuum, which takes a diffusion vacuum pump, ... [Ernst Ruska], in fact, developed the transmission electron microscope or TEM.

Michigan Tech’s new Scanning Transmission Electron Microscope lets researchers zoom in to understand the big picture at the atomic scale. ... Another function of the microscope is creating ...

The electron beam follows a vertical path through the microscope, which is held within a vacuum. The beam travels through electromagnetic fields and lenses, which focus the beam down toward the sample ...

The negative stain bench provides users with everything needed to make and stain their own sample for electron microscopy. This includes core-provided tweezers, uranyl formate stain, continuous carbon ...

The research team used monochromated electron energy-loss spectroscopy (EELS) in conjunction with a scanning transmission electron microscope (STEM). With this technique, a negatively charged electron ...