The San Francisco 49ers are hurting with an injury to Brandon Aiyuk and an illness for Deebo Samuel, who sent an emotional ...

San Francisco 49ers wide receiver Deebo Samuel has been hospitalized due to fluid in his lungs, head coach Kyle Shanahan ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee.

San Francisco 49ers receiver Deebo Samuel attempted to play through an illness during Sunday's loss to the Kansas City Chiefs ...

San Francisco 49ers star wide receiver Deebo Samuel has been hospitalized with pneumonia. He left Sunday's game vs. the Chiefs early.

A significant reason for the team's rough 3-4 start to the season has been its injuries. Superstar running back Christian ...

The San Francisco 49ers' worst fears were confirmed on Monday when tests revealed that wide receiver Brandon Aiyuk suffered a season-ending knee injury ...

Deebo Samuel is in a hospital dealing with pneumonia, meaning the the San Francisco 49ers have health concerns with their top ...

Brandon Aiyuk went down with a right knee injury in Sunday's 28-18 loss to the Kansas City Chiefs that coach Kyle Shanahan ...

The NFL trade deadline is Tuesday, Nov. 5, and 49ers coach Kyle Shanahan said San Francisco will consider all options.

San Francisco 49ers star receiver Deebo Samuel Sr. is in the hospital with pneumonia and fluid in his lungs, his head coach Kyle Shanahan announced on Monday.

Head coach Kyle Shanahan addressed reporters during a conference call on Monday, a day after the San Francisco 49ers' loss to ...