A 40-year-old man presented to the emergency department with a 5-day history of fevers, sore throat, fatigue, subjective ...

A 45-year-old woman was evaluated in the rheumatology clinic because of possible IgG4-related disease. She had polyclonal ...

Whether extended lymphadenectomy is associated with improved disease-free and overall survival, as compared with standard lymphadenectomy, among patients with localized muscle-invasive bladder ...

CAR T-cell manufacturing involves T-cell apheresis, CAR transduction, and expansion of transduced autologous or allogeneic T cells. To date, approved CAR T-cell products rely on lentiviral ...

The next U.S. president will inherit multiple epidemics with inequitably distributed effects. Kamala Harris and Donald Trump are likely to take divergent policy approaches to addressing these crises.

In order to ensure timely testing of drugs that have been granted accelerated approval, the FDA can impose civil monetary penalties on dilatory manufacturers — but has never done so. This ...

U.S. states, which are better positioned than the federal government to precisely and comprehensively address the drivers of low-value health care spending, should lead the way in establishing ...

While reproductive health has drawn the spotlight in the U.S. elections, less attention has been paid to other health policy issues, in part because of the success of the Affordable Care Act.

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

A new report from the National Academy of Medicine discusses the challenges facing U.S. biomedical research and proposes major policy changes to strengthen and reinvigorate the biomedical research ...

Excess adiposity is a major risk factor for obstructive sleep apnea. Tirzepatide, known to reduce body weight, is a potential treatment for adults with obstructive sleep apnea and obesity.